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KMID : 0360220180590080718
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Journal of the Korean Ophthalmological Society
2018 Volume.59 No. 8 p.718 ~ p.723
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Lid Wiper Epitheliopathy in Patients with Dry Eye Refractory to Conventional Medical Treatment
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Huh Jung-Ah
Woo In-Ho
Eom Young-Sub
Kang Su-Yeon
Kim Hyo-Myung
Song Jong-Suk
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Abstract
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Purpose: We evaluated the effects of lid wiper epitheliopathy on the clinical manifestations of dry eye in patients refractory to conventional medical treatment.
Methods: Forty-six patients (46 eyes) completed the subjective Ocular Surface Disease Index (OSDI), and we obtained objective measures including the tear break-up time (TBUT), the National Eye Institute (NEI) corneal staining score, tear osmolarity, and lid wiper epitheliopathy as revealed on photographs taken using a yellow filter after fluorescein instillation. The images were graded using the Korb B protocol.
Results: The mean OSDI score was 48.06 ± 21.19; 34 patients (73.9%) were had scores ≥33. Lid wiper epitheliopathy was evident in 41 (89.1%), and the epitheliopathy grade and OSDI score were correlated (r = 0.56, p < 0.01). The NEI score was also positively correlated with the OSDI score (r = 0.54, p < 0.01), but the mean value was low (1.59 ± 2.13). The OSDI score did not correlate significantly with either the TBUT or tear osmolarity (r = ?0.16, p = 0.279; r = 0.16, p = 0.298, respectively).
Conclusions: Lid wiper epitheliopathy was present in about 90% of patients with dry eye who visited our tertiary hospital, and a significant correlation was evident between the epitheliopathy grade and the OSDI score.
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KEYWORD
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Correlation, Dry eye, Lid wiper epitheliopathy, Medical, Refractory
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